Stress and Anxiety Relief
For many people stress and anxiety are the symptoms of their
high-powered day to day existence. If not managed properly, chronic
stress and anxiety may cause many disorders, including insomnia, heart
disease, Type 2 diabetes, and cognitive impairment. There are many
pharmaceutical drugs on the market that promise to bring peace of mind
and relieve the symptoms of anxiety, but many people prefer to look for
natural alternatives out of fear of side effects and possible addiction.
One of the most powerful natural antidotes to stress is L-theanine.
L-theanine (gamma-ethylamino-L-glutamic acid) is a non-protein forming
amino acid found almost exclusively in the green leaves of the tea
plant (Camellia sinensis). The only other significant source in nature
is the Boletus badius mushroom also known as Bay bolete. Among other
active compounds, Bay bolete contains substantial amounts of L-theanine.
L-theanine
was first isolated in Japan, where green tea is part of the culture
since inception of Buddhism in the 6th century. Green tea was used
traditionally by the Buddhist monks to keep them calm and awake during
long hours of meditation. Researchers found out that caffeine ingested
in green tea had a different effect on the mind and the body that had
the same amount of caffeine from coffee. The excitatory effect of
caffeine in green tea was offset by the calming action of a compound
that was named theanine. L-theanine constitutes about 50 per cent of
the dry protein weight of green tea.
L-theanine is a powerful stress and anxiety reliever. It effectively
reduces both, mental and physical, stress. About 30-40 minutes after
ingestion, it induces tranquility and a state of deep relaxation
without causing any drowsiness or forming a chemical dependence. In
fact, it helps improve attention and concentration.
L-theanine is
one of the few known substances that can easily cross the blood-brain
barrier. It exerts subtle changes in the brain chemistry by altering
the levels of serotonin, dopamine, and GABA (gamma-amino-butyric acid).
L-theanine induces state of well-being and relaxation in four ways:
- it stimulates the production of alpha waves in the brain
- it increases the levels of the inhibitory neurotransmitter GABA in the brain
- it lowers the blood pressure
- reduces heart rate
Encephalographic measurements (EEG) show that L-theanine increases the
brain activity within the alpha frequency band (8-13.9 Hz). The alpha
state of the brain indicates relaxation, relaxed focus, and increased
serotonin production. The slowest alpha waves are associated with the
so called twilight state - a deep relaxation state that is usually
experienced between sleep and waking. People who meditate begin to
access the unconscious mind at this stage of relaxation.
The
inhibitory neurotransmitter GABA is considered to be the brain's own
tranquilizer. It helps to reduce the excess of stress hormone adrenalin
and calm down. It also controls the levels of noradrenalin, dopamine,
and serotonin in the brain. Insufficient levels of GABA are associated
with anxiety, tension, depression, and insomnia. L-theanine increases
the secretion of GABA thus helping the brain to calm itself.
L-theanine
has been shown to reduce the blood pressure in individuals with
elevated blood pressure. It did not, however, affect individuals with
normal blood pressure which means that in only acts where there is lack
of balance.
Other benefits of L-Theanine
While L-theanine received the greatest attention as a natural
anti-anxiety drug, it also has many other benefits as it restores
chemical balance in the body:
-
alleviates depression
- supports concentration and mental performance
- helps focus attention on critical tasks
- improves learning
- protects the body from stress damage caused by the hormone cortisol
- improves quality of sleep when taken 30 minutes before bed
- protects the brain from damage done by glutamate and caffeine
- supports the immune system by increasing the activity of T-cells
-
assists in weight loss by promoting thermogenesis
- reduces levels of lipids in the blood
- lowers blood pressure in people with a high blood pressure
- relieves physical and mental symptoms of PMS
- protects the liver from damage caused by alcohol
- slows down the growth of certain tumors
L-theanine has remarkable cognitive effects. Research shows that
L-theanine increases brainwave activity that is normally associated
with attention and concentration. It helps to stay centered in spite of
stress. Studies show that the substance has remarkable ability to
minimize interference from distracting outside stimuli helping at the
same time to focus attention. Subjects in the study were able to
concentrate on important tasks without getting distracted.
While
L-theanine is not a sedative, it significantly improves the quality of
sleep and prolongs the duration of deep sleep. Taken about half an hour
before bed time, it helps to unwind and fall to sleep. One wakes up
rested and refreshed. L-theanine can safely be taken together with
melatonin and 5-HTP to improve sleep patterns.
L-theanine
appears to act as an antagonist to glutamate receptors and may be
useful in treating depression. Stress and depression activate stress
hormones known as glucocorticoids. These hormones disrupt brain
chemistry and affect mood and memory. Glutamate seems to play a major
role in the process. In depressed people glutamate levels in the brain
are out of balance. Based on research, drugs that suppress
glucocorticoids have been proposed as an effective treatment of
depression. L-theanine blocks certain signals produced by glutamate and
suppresses harmful effects of glucocorticoids helping to restore
chemical balance in the brain.
Research shows that L-theanine
may protect the brain from the damage
caused by a stroke. It also helps to preserve brain functions such as
blood flow in a stroke affected brain area. Moreover, L-theanine
protects brain cells against the toxic damage caused by the excitatory
neurotransmitter glutamate. After a stroke excess of glutamate in the
space between the cell receptors is believed to cause the increased
neuronal death. L-theanine appears to modulate this damage. Laboratory
tests show that there was no damage in the brains where L-theanine was
present before the stroke. These findings also bring hope to the
Alzheimer's disease
research, as the glutamate toxicity is associated with the neural
damage that occurs in Alzheimer's disease. Together with other
compounds found in tea, L-theanine counteracts the neuro-toxicity of
the harmful beta-amyloid protein commonly found in the brains of
Alzheimer's patients. It helps increase the activity of an enzyme that
breaks dawn this protein.
L-theanine has been demonstrated to
support overall cardiovascular health. It prevents lipid peroxidation
of LDL (low-density lipoprotein). Peroxidation of lipids is believed to
be one of the causes of atherosclerosis.
Japanese
researchers have found that L-theanine minimizes the harmful effect of
alcohol in the liver where alcohol is converted to extremely toxic
chemical known as acetaldehyde. L-theanine seem to accelerate the
digestion of acetaldehyde and to block the harmful free radicals. It
increases the levels of glutathione that is normally depleted by the
consumption of alcohol and restores the detoxifying capacity of the
liver.
L-theanine may also find an application in
complementary cancer therapies. It not only inhibits the growth of
certain tumors, but also enhances the activity of pirarubicin,
doxorubicin and adriamycin - drugs that are used in chemotherapy,
reducing at the same time their destructive side-effects on healthy
tissues of the patient. L-theanine seems to decrease the tumors ability
to get rid of an anti-cancer drug. More studies have to be conducted,
but the Japanese scientists T. Sugiyama and Y. Sadzuka are very
optimistic.
L-theanine is a versatile natural supplement that
helps to restore the balance in the mind and the body. It has no known
side effects. It relaxes, restores mood, and rejuvenates. In Japan,
where stress is ubiquitous and people even die from work related stress
(karoshi death), L-theanine was approved as a food additive in 1964.
There are many products on the market, but only products containing
Suntheanine® are worth buying. Suntheanine® is enzymatically
synthesized L-theanine of highest purity and efficacy. The suggested
dose is 200-400 mg a day.
Although L-theanine is safe and has
no known side-effects, please, consult your health care provider before
beginning supplementation.
By Dominique Allmon
Dominique Allmon©2012
*Information in this article is for educational purposes only and is not meant to diagnose, treat or cure a disease.
Health Benefits of L-Theanine by
Dominique Allmon is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.